icd 10 diabetes mellitus type 2 in nonobese

πŸ”₯+ icd 10 diabetes mellitus type 2 in nonobese 04 Aug 2020 Is it possible that symptoms of diabetes could materialize virtually overnight? ... that won't heal, frequent infections (including vaginal infections in some women), ...

icd 10 diabetes mellitus type 2 in nonobese I am curious whether other diabetic people have problems with high blood sugar levels after eating oatmeal or porridge? I am Type 2, and I use ...

which diabetes is autoimmune
Skip to main content

Main menu

the 1 last update 04 Aug 2020 SearchSearch

Epidemiology/Health Services Research
  1. Jessica L. Harding⇑,
  2. Meda for 1 last update 04 Aug 2020 E. PavkovMeda E. Pavkov,
  3. Edward W. Gregg and
  4. icd 10 diabetes mellitus type 2 in nonobese quizlet (πŸ‘ quiz questions) | icd 10 diabetes mellitus type 2 in nonobese how do you get ithow to icd 10 diabetes mellitus type 2 in nonobese for Nilka for 1 last update 04 Aug 2020 R. BurrowsNilka R. Burrows
  1. Division of Diabetes Translation, Centers for Disease Control and Prevention, Atlanta, GA
  1. Corresponding author: Jessica L. Harding, jharding{at}cdc.gov
Diabetes Care 2019 Aug; 42(8): icd 10 diabetes mellitus type 2 in nonobese blood sugar range chart (πŸ”₯ uk statistics) | icd 10 diabetes mellitus type 2 in nonobese quoteshow to icd 10 diabetes mellitus type 2 in nonobese for 1430-1435. https://doi.org/10.2337/dc19-0296 https://doi.org/10.2337/dc19-0296

Abstract

OBJECTIVE Nontraumatic lower-extremity amputation (NLEA) is a complication of end-stage renal disease (ESRD) and diabetes. Although recent data show that NLEA rates in the U.S. ESRD population are declining overall, trends in diabetes and diabetes subgroups remain unclear.

RESEARCH DESIGN AND METHODS We estimated annual rates of NLEA hospitalizations during 2000–2015 among >2 million adults (β‰₯18 years) with ESRD from the U.S. Renal Data System. Age, sex, and race-adjusted NLEA rates were stratified by diabetes status, age, sex, race, and level of amputation (toe, foot, below the knee, and above the knee). Time trends were assessed using Joinpoint regression with annual percent changes (APC) reported.

RESULTS Among adults with diabetes, NLEA rates declined 43.8% between 2000 and 2013 (from 7.5 to 4.2 per 100 person-years; APC βˆ’4.9, P < 0.001) and then stabilized. Among adults without diabetes, rates of total NLEAs declined 25.5% between 2000 and 2013 (from 1.6 to 1.1; APC βˆ’3.0, P < 0.001) and then stabilized. These trends appear to be driven by a slowing or stagnation in declines of minor NLEAs (toe and foot) in more recent years, while major NLEAs (above the knee) continue to decline.

CONCLUSIONS Despite an initial period of decline, this analysis documents a stall in progress in NLEA trends in recent years in a high-risk population with both ESRD and diabetes. Increased attention to preventive foot care in the ESRD population should be considered, particularly for those with diabetes.

Introduction

In 2016, 124,675 people in the U.S. began treatment for end-stage renal disease (ESRD) (i.e., kidney failure requiring dialysis or transplantation). The incidence of ESRD increased in the 1980s and 1990s and has remained stable since 2000 (1). Diabetes is the most common cause of kidney failure, accounting for 46% of all new ESRD cases in 2016 (1). The progression of diabetes to ESRD is associated with neuropathy and peripheral vascular disease (2), which, in turn, is associated with an increased risk for nontraumatic lower-extremity amputation (NLEA). Both ESRD and NLEA are serious complications of diabetes, leading to a decrease in quality of life and an increased risk for premature mortality (3).

icd 10 diabetes mellitus type 2 in nonobese by race (β˜‘ veteran) | icd 10 diabetes mellitus type 2 in nonobese therapyhow to icd 10 diabetes mellitus type 2 in nonobese for People with diabetes have an elevated risk for developing ESRD, and people with both ESRD and diabetes are at much higher risk for NLEA compared with those having either condition alone (4). In the U.S., between 1991 and 1994, the rate of NLEA in ESRD patients with diabetes was approximately six times higher than the rate of NLEA in the ESRD population without diabetes (4). In addition to diabetes, risk factors for NLEA among people with ESRD include older age, male sex, black race, and Native American the 1 last update 04 Aug 2020 heritage (4).People with diabetes have an elevated risk for developing ESRD, and people with both ESRD and diabetes are at much higher risk for NLEA compared with those having either condition alone (4). In the U.S., between 1991 and 1994, the rate of NLEA in ESRD patients with diabetes was approximately six times higher than the rate of NLEA in the ESRD population without diabetes (4). In addition to diabetes, risk factors for NLEA among people with ESRD include older age, male sex, black race, and Native American heritage (4).

The epidemiology of NLEA in people with diabetes has been explored in several reviews (3,5,6). Overall, significant reductions in NLEA incidence over time have been shown as well as reductions in the excess risk between people with and without diabetes (3,5,6). Few studies, however, have explored contemporary trends in NLEA rates among the ESRD population with and without diabetes. In the U.S. ESRD population, a relative decline in NLEA rates of 52.8% and 48.0% between 2000 and 2014 has been observed for people with and without diabetes, respectively (7). However, Franz et al. (7) did not explore NLEA rates among people with and without diabetes by key demographic subgroups such as age, sex, and race or by amputation type. In addition, this study assumed a linear trend in NLEA rates over time, which fails to identify multiple time points in which trends may change significantly in either direction or magnitude within a 15-year period.

Therefore, we analyzed trends in annual NLEA rates among the U.S. ESRD population, adding one more year of data (2015), by demographic subgroups (age, sex, and race), and examining multiple trends within the 16-year time period.

Research Design and Methods

Study Design and Population

The U.S. Renal Data System (USRDS) is a national registry of people with ESRD drawn from clinical and claims data reports submitted to the Centers for Medicare & Medicaid Services (CMS) (1). All adults aged β‰₯18 years initiating dialysis treatment and registered on the USRDS between 1996 and 2015 were included in this study. The year 1996 was chosen as the 1st year of study inclusion, as the CMS2728 form used to ascertain comorbid conditions was not required until 1995. We excluded patients for the following reasons: <18 years of age; missing CMS data; missing data on age, sex, or race; if first ESRD treatment was a transplant; renal transplant or death event occurred prior to 1 January 2000; and USRDS registration occurred on or after 31 December 2015. The final sample size was 2,060,638, made up of 16 cross-sectional populations of adults with prevalent ESRD per year between 2000 and 2015.

icd 10 diabetes mellitus type 2 in nonobese education (⭐️ vitamind3) | icd 10 diabetes mellitus type 2 in nonobese in a sentencehow to icd 10 diabetes mellitus type 2 in nonobese for NLEA Hospitalizations

NLEA hospitalizations were ascertained from CMS data from 1 January 2000 through 31 December 2015. The year 2000 was chosen as the 1st year of analysis due to the accrual of prevalent patients from 1996 onwards, allowing a large enough sample size to estimate NLEA rates in the ESRD population with and without diabetes. NLEA hospitalizations were defined using the ICD-9 Clinical Modification (ICD-9-CM) procedure codes from January 2000 through September 2015 and ICD-10-CM from October to December 2015, excluding disease codes for traumatic amputation (Supplementary Table 1). To prevent overestimation of NLEA rates due to planned multistep procedures that may occur across weeks or months, as well as recurrent amputations that may simply reflect a failure of healing of the initial amputation, we included only the highest-level amputation per patient per calendar year. NLEAs were categorized as toe, foot, below the knee (BKA), above the knee (AKA), and minor and major (Supplementary Table 1). Data are presented as annual rates of NLEAs between 2000 and 2015.

Covariates

Information on covariates was collected from CMS data. Besides demographic information, USRDS data include the date patients were first treated for ESRD with dialysis, primary cause of ESRD, some clinical measurements, and comorbidities obtained from CMS that health care providers are required by law to complete for each new patient with ESRD. In this study, diabetes was defined based on clinician-assigned primary cause of ESRD.

Statistical Analysis

icd 10 diabetes mellitus type 2 in nonobese high blood sugar symptoms (πŸ”₯ kids) | icd 10 diabetes mellitus type 2 in nonobese juicehow to icd 10 diabetes mellitus type 2 in nonobese for Differences in characteristics between adults with and without diabetes at time of dialysis initiation, and between adults initiating dialysis in 2000, 2005, or 2010, were assessed using Pearson Ο‡2 test for proportions and Student t test for means from approximately normal distributions and Wilcoxon rank sum test for skewed data.

Annual NLEA hospitalization rates, per 100 person-years, were estimated using Stata version 14.1 (StataCorp, College Station, TX). Individuals were followed from 1 January of the cohort year, or dialysis date if thereafter, to 31 December of cohort year, date of NLEA, date of renal transplant, or date of deathβ€”whichever occurred first. Annual NLEA rates were estimated using a log Poisson generalized linear model with robust SEs estimated using the delta method. All models were adjusted for age, sex, race, and ethnicity and included an offset term with log exposure time.

We used Joinpoint Trend Analysis Software version 4.5.0.1 (8) to analyze trends in annual NLEA hospitalization rates. This software uses permutation tests to identify points where linear trends change significantly in either direction or magnitude and calculates an annual percentage change (APC) for each time period identified. Statistical significance was established at P < 0.05. Trends were analyzed by diabetes, age-group (18–44, 45–64, 65–74, and β‰₯75 years of age), sex, race (white, black, and other [Native American, Asian, and other/multiracial]), and level of amputation (toe, foot, BKA, AKA, minor [below the ankle], and major [through or above the ankle]).

Results

Characteristics of the ESRD population at time of ESRD treatment initiation are shown in Table 1. In brief, compared with adults without diabetes, adults with diabetes were more likely to be women, Hispanic, and unemployed; more likely to have higher mean BMI, lower serum creatinine, lower LDL, and lower hemoglobin and serum albumin; and more likely to have comorbidities, excluding cancer and chronic obstructive pulmonary disease (COPD).

icd 10 diabetes mellitus type 2 in nonobese jogging (β˜‘ fasting blood sugar goal) | icd 10 diabetes mellitus type 2 in nonobese womenhow to icd 10 diabetes mellitus type 2 in nonobese for View the 1 last update 04 Aug 2020 this table:View this table:
Table 1

Descriptive characteristics of the ESRD population, with and without diabetes, at time of ESRD treatment initiation

Over time, there were differences in characteristics of those initiating ESRD dialysis treatment (Table 2). Compared with those initiating treatment in 2000 and 2005, those initiating ESRD treatment in 2010 were more likely to be men, older, unemployed, white, Hispanic, and current smokers. In 2010, patients were also more likely to have a higher mean BMI, higher serum albumin, lower serum creatinine, hypertension, and COPD.

View this table:
Table 2

icd 10 diabetes mellitus type 2 in nonobese explanation (πŸ‘ young adults) | icd 10 diabetes mellitus type 2 in nonobese is caused byhow to icd 10 diabetes mellitus type 2 in nonobese for Descriptive characteristics of the ESRD population at time of ESRD treatment initiation in 2000 vs. 2005 vs. 2010

Among adults with diabetes, NLEA hospitalization rates declined 43.8% between 2000 and 2013 (from 7.5 to 4.2 per 100 person-years; APC βˆ’4.9 [95% CI βˆ’5.5, βˆ’4.3], P < 0.001) and then stabilized (Table 3). Minor and major NLEAs declined for 1 last update 04 Aug 2020 between 2000 and 2012, and 2000 and 2013, respectively, and then no further declines were observed.Among adults with diabetes, NLEA hospitalization rates declined 43.8% between 2000 and 2013 (from 7.5 to 4.2 per 100 person-years; APC βˆ’4.9 [95% CI βˆ’5.5, βˆ’4.3], P < 0.001) and then stabilized (Table 3). Minor and major NLEAs declined between 2000 and 2012, and 2000 and 2013, respectively, and then no further declines were observed.

View the 1 last update 04 Aug 2020 this table:View this table:
Table 3

Hospitalization rates of total, minor, and major NLEA and APC among the ESRD population, by diabetes status, 2000–2015

For all age-groups, excluding 18–44 years, and in men and women, NLEA rates declined in the first period and then no significant change occurred in the second period (Table 4). By race, significant declines in NLEA rates were observed for blacks and β€œother race” for the entire period, but among whites, declines occurred between 2000 and 2013 and then no further significant declines were observed.

icd 10 diabetes mellitus type 2 in nonobese permanently (πŸ”₯ effects) | icd 10 diabetes mellitus type 2 in nonobese paperhow to icd 10 diabetes mellitus type 2 in nonobese for View this table:
Table 4

Hospitalization rates for any NLEA in people with ESRD, by diabetes status, and APC, by age, sex, race, and level of amputation

By level of amputation, declines in NLEAs of the toe for 1 last update 04 Aug 2020 and BKA were observed between 2000 and 2012, with no further declines thereafter. NLEAs of the foot declined from 2000 to 2013 and then increased nonsignificantly between 2013 and 2015 (APC 8.9 [βˆ’2.1, 21.1], P = 0.11). NLEAs for AKA decreased from 2002 onwards (Table 4).By level of amputation, declines in NLEAs of the toe and BKA were observed between 2000 and 2012, with no further declines thereafter. NLEAs of the foot declined from 2000 to 2013 and then increased nonsignificantly between 2013 and 2015 (APC 8.9 [βˆ’2.1, 21.1], P = 0.11). NLEAs for AKA decreased from 2002 onwards (Table 4).

Among people without diabetes, rates of first NLEA declined 25.5% between 2000 and 2013 (from 1.6 to 1.2; APC βˆ’3.0 [βˆ’3.6, βˆ’2.3], P < 0.001) and then remained stable (Table 3). By age, significant increases were observed in those aged 18–44 years (APC 3.8 [2.4, 5.1], P < 0.001), no change was seen in those aged 45–64 years, and declines were observed in those aged 65–74 and 75+ years between 2000 and 2013, followed by no change. By sex, race, and level of amputation, patterns were similar in people with and without diabetes (Table 4), but the absolute magnitude of risk remained much higher in people with diabetes across all subgroups.

Conclusions

In this analysis, we note several patterns in rates of NLEA in adults with ESRD. First, initial declines in NLEA rates have been followed by a recent stagnation. This trend appears to be driven by a slowing or stagnation in declines of minor NLEAs (toe and foot) in more recent years while major NLEAs (above the knee) continue to decline. Second, a lack of decline in NLEAs in more recent years was seen across most subgroups of age and sex and among white adults with and without diabetes. Third, although trend patterns are similar in the ESRD population with and without diabetes, the absolute magnitude in NLEA risk remains substantially higher in people with diabetes.

The current study adds important complementary data to what is already known about NLEA rates in the U.S. ESRD population (7). Here, we address the concerning lack of decline in NLEA rates in recent years and highlight important subgroups within the population that may benefit most from preventive care and treatment. Trends observed in the current study are similar to those shown in a nationally representative study of people with diabetes in the general U.S. population (9). Geiss et al. (9) reported a 43% reduction in NLEA rates between 2000 and 2009 (from 5.4 to 3.1 per 1,000 people, P < 0.001) and then a 41% increase between 2009 and 2014 (from 3.1 to 4.3, P < 0.002). This was similarly driven by increasing rates of minor NLEAs and disproportionally affected younger and the 1 last update 04 Aug 2020 middle-aged adults. In contrast, among the general U.S. population without diabetes, NLEA rates declined 28% between 2000 and 2014 (from 0.24 to 0.17 per 1,000 people, P < 0.001) (9). As of 2014, people with ESRD and diabetes in the current study still had a 6- and 150-fold increased rate of NLEA, as compared with the general population with and without diabetes, respectively, as reported in the study by Geiss et al. (9).The current study adds important complementary data to what is already known about NLEA rates in the U.S. ESRD population (7). Here, we address the concerning lack of decline in NLEA rates in recent years and highlight important subgroups within the population that may benefit most from preventive care and treatment. Trends observed in the current study are similar to those shown in a nationally representative study of people with diabetes in the general U.S. population (9). Geiss et al. (9) reported a 43% reduction in NLEA rates between 2000 and 2009 (from 5.4 to 3.1 per 1,000 people, P < 0.001) and then a 41% increase between 2009 and 2014 (from 3.1 to 4.3, P < 0.002). This was similarly driven by increasing rates of minor NLEAs and disproportionally affected younger and middle-aged adults. In contrast, among the general U.S. population without diabetes, NLEA rates declined 28% between 2000 and 2014 (from 0.24 to 0.17 per 1,000 people, P < 0.001) (9). As of 2014, people with ESRD and diabetes in the current study still had a 6- and 150-fold increased rate of NLEA, as compared with the general population with and without diabetes, respectively, as reported in the study by Geiss et al. (9).

The extremely high risk for NLEA among people with ESRD and diabetes can be attributed, in part, to more severe neuropathy and peripheral vascular disease, complicated by poor wound healing, foot ulcers, and gangrene (10–14). Further, an initial NLEA is associated with a higher risk of subsequent NLEA to the same or other limb. In a study of people with diabetes, among 435 patients who had an initial NLEA, 19.8% had a recurrent NLEA (15). In our population of adults with ESRD and a previous amputation, 42.6% and 35.0% with and without diabetes, respectively, had a recurrent amputation between 2001 and 2015. In addition to a high level of comorbidities among the ESRD population, poor survival rates after NLEA have been reported in several studies (4,16–19). In a study of U.S. Medicare ESRD beneficiaries, cumulative survival at 1-year post-NLEA was only 49.3% compared with 78.7% for ESRD patients who had not had an NLEA (4). Collectively, this highlights a group of patients with a disproportionately high risk for NLEA, morbidity, and mortality. As individuals with ESRD are in frequent contact with the health care system to obtain renal replacement therapy, there are numerous opportunities to reduce the rates of NLEA with preventive foot care and early detection of foot problems (4).

Reasons for the observed slowing in NLEA trends in the U.S. are unclear, although several hypotheses exist. First, a flattening of hospitalization rates of minor NLEA may suggest changes in clinical practice that favor earlier minor NLEAs to prevent major NLEAs in the future. This hypothesis is supported in our study with declines or stabilizations in recurrent major NLEAs (Supplementary Table 2). Second, it is possible that the incident ESRD population may be more β€œsick” as compared with previous years, leading to an increased risk for complications such as NLEA. However, when we compared characteristics of those initiating ESRD in 2000 vs. 2005 vs. 2010, findings were mixed. Although new ESRD patients in 2010 were more likely to have hypertension, COPD, a higher BMI, and be current smokers, they also had higher serum albumin, which is associated with a decreased risk for NLEA in people with ESRD (10). Further, although these differences were statistically significant, the absolute differences between those initiating ESRD treatment in 2000 vs. 2010 were small. Third, it is possible that stagnating NLEA rates are due to shortcomings in early prevention practices (i.e., physician and patient self-management education, use of appropriate footwear, and identification of high-risk feet [20]), leading to an increase in the prevalence of foot problems (ulcers and infection) that are known to disproportionality affect dialysis patients with diabetes (21). It is also possible that delayed access to treatment has led to a greater severity of foot problems, leading to a greater need for amputation. Other alternative explanations include changes in coding practice for NLEA procedures and a possible increase in coding of diabetes on NLEA hospitalizations. However, it is unclear why these factors should have a greater impact on different subgroups such as younger adults without diabetes and whites.

Although we used a large national database of individuals with ESRD linked to hospitalization records, some limitations should be considered. We used clinician-assigned β€œprimary cause” of ESRD to assign diabetes status, and so it is possible we have over- or underestimated the proportion of ESRD attributed to diabetes (1). We also used ICD-9-CM between January 2000 and September 2015 to identify NLEAs. ICD-9-CM is limited by its inability to distinguish between left and right legs and between toes. A shift to ICD-10-CM for the last 3 months of the study period may have affected our observed rates. However, observed changes in trends occurred before this period, and therefore, it is unlikely that this coding shift influenced the overall patterns that we observed in this study.

Despite an initial period of decline, this analysis documents a discouraging stall in progress in NLEA trends in recent years in a high-risk population with both ESRD and diabetes in the U.S. A better understanding of the factors driving these changes may help to reverse these recent trends and sustain positive future trends. In the meantime, continued efforts to improve access to and uptake of preventive foot care, improve diabetes self-management, and promote education might be a priority for ESRD patients, particularly among those with diabetes.

Article Information

Acknowledgments. The data reported here have been supplied by the USRDS.

The interpretation and reporting of these data are the responsibility of the authors and in no way should be seen as an official policy or interpretation of the U.S. government.

Duality of Interest. No potential conflicts of interest relevant to this article were reported.

Author Contributions. J.L.H. conducted the analyses, interpreted the results, and wrote the manuscript. M.E.P. and E.W.G. contributed to interpretation and reviewed the manuscript. N.R.B. conceptualized the manuscript, contributed to interpretation, and reviewed the manuscript. J.L.H. is the guarantor of this work and, as such, had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Prior Presentation. Parts of this study were presented at the 78th Scientific Sessions of the American Diabetes Association, Orlando, FL, 22–26 June 2018.

Footnotes

  • icd 10 diabetes mellitus type 2 in nonobese google scholar (⭐️ hereditary) | icd 10 diabetes mellitus type 2 in nonobese natural treatment curehow to icd 10 diabetes mellitus type 2 in nonobese for This article contains Supplementary Data online at http://care.diabetesjournals.org/lookup/suppl/doi:10.2337/dc19-0296/-/DC1.

  • icd 10 diabetes mellitus type 2 in nonobese undiagnosed (⭐️ care plan) | icd 10 diabetes mellitus type 2 in nonobese good foodhow to icd 10 diabetes mellitus type 2 in nonobese for The findings and conclusions in this report are those of the authors and do not necessarily represent the official position of the Centers for Disease Control and Prevention.

  • Received February 13, 2019.
  • Accepted May 7, 2019.
  • Β© 2019 by the American Diabetes Association.
http://www.diabetesjournals.org/content/license

Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. More information is available at http://www.diabetesjournals.org/content/license.

References

  1. ↡
    1. United States Renal Data System
    . USRDS Annual Data Report: Epidemiology of Kidney Disease in the United States. Bethesda, MD, icd 10 diabetes mellitus type 2 in nonobese menu (πŸ‘ hypoglycemia) | icd 10 diabetes mellitus type 2 in nonobese with weight losshow to icd 10 diabetes mellitus type 2 in nonobese for National Institutes of the 1 last update 04 Aug 2020 Health National Institute of Diabetes and Digestive and Kidney DiseasesNational Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases, 2018
  2. ↡
    1. icd 10 diabetes mellitus type 2 in nonobese permanently (πŸ”΄ insulin resistance) | icd 10 diabetes mellitus type 2 in nonobese ketoacidosishow to icd 10 diabetes mellitus type 2 in nonobese for Fernando the 1 last update 04 Aug 2020 DJDJ,
    2. Hutchison A,
    3. Veves A,
    4. Gokal icd 10 diabetes mellitus type 2 in nonobese ribbon (πŸ”΄ experience) | icd 10 diabetes mellitus type 2 in nonobese diagnostic procedureshow to icd 10 diabetes mellitus type 2 in nonobese for R,
    5. Boulton AJ
    . Risk factors for non-ischaemic foot ulceration in diabetic nephropathy. Diabet Med 1991; for 1 last update 04 Aug 2020 88:223–225pmid:1828736
  3. ↡
    1. for 1 last update 04 Aug 2020 NarresNarres M,
    2. Kvitkina T,
    3. Claessen H, icd 10 diabetes mellitus type 2 in nonobese dinner recipes (πŸ”΄ hyperglycemia) | icd 10 diabetes mellitus type 2 in nonobese guidelines 2020how to icd 10 diabetes mellitus type 2 in nonobese for et al
    . Incidence of lower extremity amputations in the diabetic compared with the non-diabetic population: a the 1 last update 04 Aug 2020 systematic reviewIncidence of lower extremity amputations in the diabetic compared with the non-diabetic population: a systematic review. PLoS One 2017;12:e0182081pmid:28846690
  4. ↡
    1. the 1 last update 04 Aug 2020 EggersEggers PW,
    2. for 1 last update 04 Aug 2020 GohdesGohdes D,
    3. Pugh J
    . Nontraumatic lower extremity amputations in the Medicare end-stage renal disease population. Kidney Int 1999; for 1 last update 04 Aug 2020 5656:1524–1533pmid:10504504
  5. ↡
    1. Carinci F,
    2. Massi Benedetti M,
    3. Klazinga NS,
    4. Uccioli L
    . Lower extremity amputation rates in people with diabetes as an indicator of health systems performance. A critical appraisal of the data collection 2000-2011 by the Organization for Economic Cooperation and Development (OECD). Acta Diabetol 2016;53:825–832pmid:27443839
  6. ↡
    1. icd 10 diabetes mellitus type 2 in nonobese experience (β˜‘ intervention) | icd 10 diabetes mellitus type 2 in nonobese vegetarian diethow to icd 10 diabetes mellitus type 2 in nonobese for Moxey PW,
    2. Gogalniceanu icd 10 diabetes mellitus type 2 in nonobese nice (πŸ”₯ medications) | icd 10 diabetes mellitus type 2 in nonobese bornhow to icd 10 diabetes mellitus type 2 in nonobese for for 1 last update 04 Aug 2020 PP,
    3. Hinchliffe RJ, et al
    . Lower extremity amputations--a review of global variability in for 1 last update 04 Aug 2020 incidenceLower extremity amputations--a review of global variability in incidence. Diabet Med 2011;28:icd 10 diabetes mellitus type 2 in nonobese nursing (πŸ‘ with hyperglycemia) | icd 10 diabetes mellitus type 2 in nonobese genetics naturehow to icd 10 diabetes mellitus type 2 in nonobese for 1144–1153icd 10 diabetes mellitus type 2 in nonobese guidelines 2020 (πŸ‘ google scholar) | icd 10 diabetes mellitus type 2 in nonobese bedtime snackshow to icd 10 diabetes mellitus type 2 in nonobese for pmid:21388445
  7. ↡
    1. Franz D,
    2. icd 10 diabetes mellitus type 2 in nonobese facts (πŸ”΄ young adults early death) | icd 10 diabetes mellitus type 2 in nonobese for dummieshow to icd 10 diabetes mellitus type 2 in nonobese for Zheng Y,
    3. the 1 last update 04 Aug 2020 LeeperLeeper NJ,
    4. Chandra V,
    5. Montez-Rath M,
    6. icd 10 diabetes mellitus type 2 in nonobese hacks (β˜‘ natural) | icd 10 diabetes mellitus type 2 in nonobese insulinhow to icd 10 diabetes mellitus type 2 in nonobese for Chang TI
    . Trends in rates of lower extremity amputation among patients with end-stage renal disease who receive dialysis. JAMA Intern Med the 1 last update 04 Aug 2020 20182018;178:1025–1032pmid:29987332
  8. ↡
    Division of Cancer Control & Population Sciences, National Cancer Institute. Joinpoint trend analysis software [Internet]. Available from https://surveillance.cancer.gov/joinpoint/. Accessed 12 February 2019
  9. ↡
    1. Geiss LGeiss L,
    2. Li the 1 last update 04 Aug 2020 YY,
    3. icd 10 diabetes mellitus type 2 in nonobese logbook (⭐️ nutrition) | icd 10 diabetes mellitus type 2 in nonobese therapeutichow to icd 10 diabetes mellitus type 2 in nonobese for Hora I,
    4. Albright A,
    5. Rolka DRolka D,
    6. Gregg icd 10 diabetes mellitus type 2 in nonobese blood sugar levels (πŸ”₯ kidshealth) | icd 10 diabetes mellitus type 2 in nonobese episodehow to icd 10 diabetes mellitus type 2 in nonobese for EW
    . Resurgence of diabetes-related nontraumatic lower-extremity amputation in the young and middle-aged adult U.S. population. Diabetes Care 2019;42:50–54pmid:30409811
  10. ↡
    1. icd 10 diabetes mellitus type 2 in nonobese kidney pain (πŸ”₯ treatment) | icd 10 diabetes mellitus type 2 in nonobese zero to finalshow to icd 10 diabetes mellitus type 2 in nonobese for Pecoraro icd 10 diabetes mellitus type 2 in nonobese lifestyle (πŸ”΄ youtube) | icd 10 diabetes mellitus type 2 in nonobese vitamin dhow to icd 10 diabetes mellitus type 2 in nonobese for RE,
    2. Reiber GE,
    3. icd 10 diabetes mellitus type 2 in nonobese autoimmune (β˜‘ nutrition) | icd 10 diabetes mellitus type 2 in nonobese natural dressingshow to icd 10 diabetes mellitus type 2 in nonobese for Burgess EM
    . icd 10 diabetes mellitus type 2 in nonobese naturally with diet (⭐️ wanna) | icd 10 diabetes mellitus type 2 in nonobese carbohydratehow to icd 10 diabetes mellitus type 2 in nonobese for Pathways to diabetic limb amputation. Basis for prevention. Diabetes Care 1990;13:513–521icd 10 diabetes mellitus type 2 in nonobese quora (πŸ”₯ normal) | icd 10 diabetes mellitus type 2 in nonobese juicehow to icd 10 diabetes mellitus type 2 in nonobese for pmid:2351029
  11. Boyko EJ, Monteiro-Soares M, Wheeler SGB. Peripheral arterial disease, foot ulcers, lower extremity amputations and diabetes. Chapter 20. In Diabetes in America. 3rd ed. Bethesda, MD, National Institutes of Health, 2017 (NIH publ. no. 17-1468)
    1. Yue DK,
    2. McLennan S,
    3. Marsh M, et al
    . Effects of experimental diabetes, uremia, and malnutrition on wound healing. Diabetes 1987;36:295–icd 10 diabetes mellitus type 2 in nonobese lunch (πŸ‘ new zealand) | icd 10 diabetes mellitus type 2 in nonobese home remedieshow to icd 10 diabetes mellitus type 2 in nonobese for 299pmid:3803737
    1. Game FL,
    2. Chipchase SY,
    3. Hubbard RHubbard R,
    4. Burden RP,
    5. Jeffcoate WJ
    . Temporal association between the incidence of foot ulceration and the start of dialysis in diabetes mellitus. Nephrol Dial Transplant 2006;21:3207–3210pmid:16877485
  12. ↡
    1. icd 10 diabetes mellitus type 2 in nonobese natural treatment cure (β˜‘ symptoms in children) | icd 10 diabetes mellitus type 2 in nonobese eventshow to icd 10 diabetes mellitus type 2 in nonobese for Ndip A,
    2. icd 10 diabetes mellitus type 2 in nonobese injection (⭐️ zero carb) | icd 10 diabetes mellitus type 2 in nonobese eventshow to icd 10 diabetes mellitus type 2 in nonobese for icd 10 diabetes mellitus type 2 in nonobese statistics (πŸ‘ can drink alcohol) | icd 10 diabetes mellitus type 2 in nonobese on insulinhow to icd 10 diabetes mellitus type 2 in nonobese for Lavery LA,
    3. Lafontaine J, et al
    . High levels of foot ulceration and amputation risk in a multiracial cohort of diabetic patients on dialysis therapy. Diabetes Care 2010;33: the 1 last update 04 Aug 2020 878878–880pmid:20067975
  13. ↡
    1. Borkosky the 1 last update 04 Aug 2020 SLSL,
    2. Roukis the 1 last update 04 Aug 2020 TSTS
    . icd 10 diabetes mellitus type 2 in nonobese zero to finals (πŸ”΄ doctor near me) | icd 10 diabetes mellitus type 2 in nonobese vitamind3how to icd 10 diabetes mellitus type 2 in nonobese for Incidence of re-amputation following partial first ray amputation associated with diabetes mellitus and peripheral sensory neuropathy: a systematic review. Diabet Foot Ankle 2012;3:1pmid:22396832
  14. ↡
    1. for 1 last update 04 Aug 2020 DossaDossa CD,
    2. Shepard AD,
    3. Amos AM, et al
    . Results of lower extremity amputations in patients with end-stage renal disease. J Vasc Surg 1994;20:14–icd 10 diabetes mellitus type 2 in nonobese mellitus without complication (⭐️ too much insulin) | icd 10 diabetes mellitus type 2 in nonobese ketones in urinehow to icd 10 diabetes mellitus type 2 in nonobese for 19pmid:8028083
    1. icd 10 diabetes mellitus type 2 in nonobese numbers (πŸ‘ reddit) | icd 10 diabetes mellitus type 2 in nonobese variationhow to icd 10 diabetes mellitus type 2 in nonobese for Fleming LWFleming LW,
    2. Stewart CP,
    3. icd 10 diabetes mellitus type 2 in nonobese exhaustion (πŸ‘ life expectancy) | icd 10 diabetes mellitus type 2 in nonobese injectionhow to icd 10 diabetes mellitus type 2 in nonobese for Henderson IS,
    4. Jain AS
    . Limb amputation on renal replacement therapy. Prosthet Orthot Int icd 10 diabetes mellitus type 2 in nonobese diet plan lose weight (πŸ‘ kids) | icd 10 diabetes mellitus type 2 in nonobese crampinghow to icd 10 diabetes mellitus type 2 in nonobese for 2000;icd 10 diabetes mellitus type 2 in nonobese ketosis (πŸ”₯ hands) | icd 10 diabetes mellitus type 2 in nonobese nature reviewhow to icd 10 diabetes mellitus type 2 in nonobese for 24:7–12pmid:10855433pmid:10855433
    1. McGrath NMMcGrath NM,
    2. Curran BA
    . icd 10 diabetes mellitus type 2 in nonobese carbs allowed per day (β˜‘ qualify for fmla) | icd 10 diabetes mellitus type 2 in nonobese occurhow to icd 10 diabetes mellitus type 2 in nonobese for Recent commencement of dialysis is a risk factor for lower-extremity amputation in a high-risk diabetic population. Diabetes Care 2000;23: for 1 last update 04 Aug 2020 432432–433pmid:10868890
  15. ↡
    1. Morbach S,
    2. Quante C,
    3. Ochs HR,
    4. icd 10 diabetes mellitus type 2 in nonobese autoimmune (⭐️ sugar level) | icd 10 diabetes mellitus type 2 in nonobese testhow to icd 10 diabetes mellitus type 2 in nonobese for Gaschler F,
    5. Pallast JMPallast JM,
    6. icd 10 diabetes mellitus type 2 in nonobese carbs allowed per day (πŸ”΄ age of onset) | icd 10 diabetes mellitus type 2 in nonobese patchhow to icd 10 diabetes mellitus type 2 in nonobese for Knevels U
    . Increased risk of lower-extremity amputation among Caucasian diabetic patients on dialysis. Diabetes Care 2001;24:icd 10 diabetes mellitus type 2 in nonobese recommendations (πŸ”₯ juvenile) | icd 10 diabetes mellitus type 2 in nonobese diagnostichow to icd 10 diabetes mellitus type 2 in nonobese for 1689–1690pmid:11522723
  16. ↡
    1. for 1 last update 04 Aug 2020 LaveryLavery LA,
    2. Hunt NAHunt NA,
    3. Lafontaine JLafontaine J,
    4. Baxter CL,
    5. for 1 last update 04 Aug 2020 NdipNdip A,
    6. Boulton icd 10 diabetes mellitus type 2 in nonobese ribbon (πŸ”₯ natural remedy) | icd 10 diabetes mellitus type 2 in nonobese kidneyhow to icd 10 diabetes mellitus type 2 in nonobese for for 1 last update 04 Aug 2020 AJAJ
    . Diabetic foot prevention: a neglected opportunity in high-risk patients. Diabetes Care 2010;33: the 1 last update 04 Aug 2020 14601460–1462pmid:20424223
  17. ↡
    1. Lavery LA,
    2. Lavery DCLavery DC,
    3. the 1 last update 04 Aug 2020 HuntHunt NA,
    4. La Fontaine JLa Fontaine J,
    5. icd 10 diabetes mellitus type 2 in nonobese cause hypertension (πŸ”΄ carb count) | icd 10 diabetes mellitus type 2 in nonobese characteristicshow to icd 10 diabetes mellitus type 2 in nonobese for Ndip A,
    6. Boulton AJ
    . Amputations and foot-related hospitalisations disproportionately affect dialysis patients. Int Wound J 2015;12:523–526icd 10 diabetes mellitus type 2 in nonobese carbs allowed per day (πŸ”₯ natural diet recommendations) | icd 10 diabetes mellitus type 2 in nonobese crampinghow to icd 10 diabetes mellitus type 2 in nonobese for pmid:24103293
View Abstract
Sign In to Email Alerts with your Email Address

Thank you for your interest in spreading the word about Diabetes Care.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
(Your Name) has forwarded a page to you from Diabetes Care
(Your Name) thought you would like to see this page from the Diabetes Care web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Trends of Nontraumatic Lower-Extremity Amputation in End-Stage Renal Disease and Diabetes: United States, 2000–2015
icd 10 diabetes mellitus type 2 in nonobese youth (πŸ”΄ definition) | icd 10 diabetes mellitus type 2 in nonobese reversalhow to icd 10 diabetes mellitus type 2 in nonobese for Jessica L. Harding, Meda E. Pavkov, icd 10 diabetes mellitus type 2 in nonobese ncbi (πŸ”₯ explanation) | icd 10 diabetes mellitus type 2 in nonobese causeshow to icd 10 diabetes mellitus type 2 in nonobese for Edward W. Gregg, Nilka for 1 last update 04 Aug 2020 R.Nilka R. Burrows
Diabetes Care Aug 2019, 42 (8) 1430-1435; icd 10 diabetes mellitus type 2 in nonobese children (β˜‘ hands) | icd 10 diabetes mellitus type 2 in nonobese treatment nihhow to icd 10 diabetes mellitus type 2 in nonobese for DOI: 10.2337/dc19-0296

Trends of Nontraumatic Lower-Extremity Amputation in End-Stage Renal Disease and Diabetes: United States, 2000–2015
Jessica L. Harding, Meda E. Pavkov, Edward W. for 1 last update 04 Aug 2020 GreggGregg, Nilka R. icd 10 diabetes mellitus type 2 in nonobese treatments google search (⭐️ expected findings) | icd 10 diabetes mellitus type 2 in nonobese natural treatment curehow to icd 10 diabetes mellitus type 2 in nonobese for Burrows
Diabetes Care Aug 2019, 42 (8) 1430-1435; icd 10 diabetes mellitus type 2 in nonobese beta cells (⭐️ straight talk) | icd 10 diabetes mellitus type 2 in nonobese untreatedhow to icd 10 diabetes mellitus type 2 in nonobese for DOI: 10.2337/dc19-0296
icd 10 diabetes mellitus type 2 in nonobese characteristics (πŸ”΄ natural treatment) | icd 10 diabetes mellitus type 2 in nonobese symptoms nhshow to icd 10 diabetes mellitus type 2 in nonobese for